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2020-06-22T10:44:54.000Z

Can daratumumab overcome the negative prognostic impact of high-risk cytogenetics? (II)

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During the 25th Congress of the European Hematology Association (EHA), the MM Hub spoke to Luciano Costa, University of Alabama at Birmingham, Birmingham, US. We asked: Can daratumumab (dara) overcome the negative prognostic impact of high-risk cytogenetics?

Dara has impacted the lives of patients with both newly diagnosed multiple myeloma (NDMM) and relapsed/refractory disease. However, the clinical activity of dara is yet to be determined in patients with NDMM and high-risk cytogenetics.

At this year's virtual EHA Annual Congress, results will be presented from a meta analysis of patients with high-risk cytogenetics treated in trials evaluating an MM backbone treatment ± dara. Here, Luciano Costa highlights the benefit of dara observed in this setting and other key results.

Can daratumumab overcome the negative prognostic impact of high-risk cytogenetics?

Your opinion matters

For a patient with triple-class exposed RRMM and high-risk cytogenetics, which of the following treatments would you select next, assuming all are available?
1 vote - 54 days left ...

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