All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the International Myeloma Foundation or HealthTree for Multiple Myeloma.
The Multiple Myeloma Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy
Join our
Treating classical Hodgkin lymphoma: Spotlight on targeted therapies
with Gilles Salles, Paul Bröckelmann, and Ann S. LaCasce
Saturday, November 2, 2024
8:50-9:50 CET
This independent educational activity is sponsored by Takeda. All content is developed independently by the faculty. Funders are allowed no direct influence on the content of this activity.
The Multiple Myeloma Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the Multiple Myeloma Hub cannot guarantee the accuracy of translated content. The Multiple Myeloma Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
The Multiple Myeloma Hub is an independent medical education platform, sponsored by Bristol Myers Squibb, GSK, Pfizer, Roche and Sanofi. The levels of sponsorship listed are reflective of the amount of funding given. Digital educational resources delivered on the Multiple Myeloma Hub are supported by an educational grant from Janssen Biotech, Inc. View funders.
Conditional approval granted to cilta-cel by the EC
On May 26, 2022, the European Commission (EC) granted a conditional marketing authorization to ciltacabtagene autoleucel (cilta-cel) for the treatment of patients with relapsed/refractory multiple myeloma (MM).1 This decision is made 2 months after the favorable opinion of the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP).
Cilta-cel’s approval is based on the results of the CARTITUDE-1 trial and depends on the provision of comprehensive and long-term data at a later stage. The current indication is for treating adult patients with relapsed/refractory MM who have received ≥3 prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 antibody, and have demonstrated disease progression on the last therapy.1
Updated data from both the CARTITUDE-1 and CARTITUDE-2 trials are expected to be presented at the upcoming 2022 American Society of Clinical Oncology (ASCO) Annual Meeting and European Hematology Association (EHA)2022 Hybrid Congress.2,3
Review here the ongoing and planned clinical trials investigating cilta-cel for the treatment of patients with MM.
- European Commission grants conditional approval of CARVYKTI® (ciltacabtagene autoleucel), Janssen’s first cell therapy, for the treatment of patients with relapsed and refractory multiple myeloma. https://www.janssen.com/european-commission-grants-conditional-approval-carvykti-ciltacabtagene-autoleucel-janssens-first. Published May 26, 2022. Accessed May 26, 2022.
- American Society of Clinical Oncology (ASCO). 2022 ASCO Annual Meeting Scheduled Sessions. https://meetings.asco.org/meetings/2022-asco-annual-meeting/288/program-guide/scheduled-sessions. Published Apr 27, 2022. Accessed May 26, 2022.
- European Hematology Association (EHA). EHA2022 Hybrid Congress Program. https://ehaweb.org/congress/eha2022-hybrid/program/program-by-day/. Published May 12, 2022. Accessed May 26, 2022.
Your opinion matters
47 votes - 9 days left ...
Related articles
Newsletter
Subscribe to get the best content related to multiple myeloma delivered to your inbox